Evaluation of a Patient with Extremely High Mean Corpuscular Hemoglobin and Mean Corpuscular Hemoglobin Concentration
نویسندگان
چکیده
منابع مشابه
Thalassemia and Hemoglobinopathy Despite Normal Level of Hemoglobin Concentration and Normal Mean Corpuscular Volume
The small mean corpuscular volume (MCV) of red blood cell is one of the indicators for thalassemia and hemoglobinopathy screening. As other screening methods, it may have some degrees of limitation. The retrospective study was performed among 104 patients who had various kinds of thalassemia or hemoglobinopathy despite having normal hemoglobin (Hb) concentration and normal mean corpuscular volu...
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Mean corpuscular hemoglobin concentration (MCHC), a parameter that is reported as a part of a standard complete blood count by automated analyzer, is a measure of the concentration of hemoglobin in a given volume of packed red blood cell. Values of MCHC significantly above reference range are not physiologically possible due to limitations on solubility of hemoglobin. The high MCHC can give us ...
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We have developed methodology that allows comparison of the mean corpuscular hemoglobin (MCH) of fetal hemoglobin (HbF)-containing red cells (F cells) with the MCH of non-F cells from the same individual. To do this, suspensions of peripheral blood erythrocytes and their internal contents are fixed with an imidodiester, dimethyl-3,3'-dithiobispropionimidate dihydrochloride (DTBP). Thereafter fi...
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This investigation is concerned with determinations of red blood cell density and mean corpuscular hemoglobin concentration in man, and with their bearing on the problem of red cell structure. At first it seemed that both the density and the quantity of hemoglobin in unit volume of red blood cells would be simple to measure, but a detailed investigation brought several unexpected difficulties t...
متن کاملStorage of blood and the mean corpuscular volume.
The mean corpuscular volume (MCV) of blood after storage for up to 24 days under various temperature conditions in ethylene diamine tetracetic acid, acid citrate dextrose, citrate phosphate dextrose, and Alsever's solution was measured using the Coulter S. Storage of blood overnight at 23 degrees centigrade increased the MCV, while there was no significant change after similar storage at 4 degr...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2020
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/hvz036